Recently, many of bio related institutes and industries are approaching their research applying Magnetic Beads. They use this material either from cell test experiment or DNA purification for disease monitoring as well as developing the treatments. The Magnetic Beads are with appropriate functional group the surface of magnetic beads. With the functional group, magnetic beads DNA, RNA, protein and specific cell, and then external Magnetic field, moved for isolation.
Magnetic Beads are a highly efficient tool for nucleic acids purification
DNA/RNA affinity to Magnetic Beads (Uniform disperse super-paramagnetic particles) is used for separation
Magnetic Beads are mixed with naked DNA/RNA in salt-containing buffer
DNA/RNA is bound to Magnetic Beads co-aggregately
By magnetic separation, highly enriched DNA/RNA preparations are obtained in the matter of minutes
Magnetic Beads is highly suitable for automation since it requires no centrifugation, vacuum filtration procedures
Sizes of Magnetic Beads are 1 - 5
Uniform Disperse Size Distribution of Magnetic Beads
Sphere Form of Silica coated Magnetic Beads
Excellent Efficiency of DNA/RNA Purification
Rapid Purification Method using Magnetic Beads.
Magnetic DNA/RNA Purification
Magnetic Protein Separation
Magnetic Antibody Separation
Magnetic Cell Isolation
DNA/RNA Purification Application
First, get the sample to work on Lysis reaction and then put Magnetic Beads to combine decomposed DNA together with Magnetic Beads. Fix Magnetic Beads with external Magnetic field to wash the solution and then elute DNA or RNA from Magnetic Beads. Using Magnetic Beads to use in purification is much faster to separate DNA compare to an existing method.
Figure 1. The steps of DNA separation by silica coated magnetic beads
Electrophoresis Results of purified DNA
Figure 2. Electrophoresis image of amplification of purified genomic DNA by silica coated magnetic beads
Comparison of viral RNA Prep Kit Quality
Figure 3. Comparison of viral RNA Prep Kit Quality using WHO HIV-1 working standard (PWS-1,2,3) serums(Q1, Q2: Q company, B1, B2: Bioneer)
'AccyBeadTM Silica Coated Magnetic Beads technology' is covered under Korea patent application 10-2008-0013545 and its corresponding international patent application.
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